Neutroxantina

Neutroxantina - General Information

A theophylline derivative with broncho- and vasodilator properties. It is used in the treatment of asthma, cardiac dyspnea, and bronchitis. [PubChem]

Pharmacology of Neutroxantina

Neutroxantina, a xanthine derivative, is a bronchodilator used for relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema. Neutroxantina is a xanthine derivative with pharmacologic actions similar to theophylline and other members of this class of drugs. Its primary action is that of bronchodilation, but it also exhibits peripheral vasodilatory and other smooth muscle relaxant activity to a lesser degree.

Neutroxantina for patients

Neutroxantina Interactions

Synergism between xanthine bronchodilators (e.g., theophylline), ephedrine, and other sympathomimetic bronchodilators has been reported. This should be considered whenever these agents are prescribed concomitantly.

Concurrent administration of dyphylline and probenecid, which competes for tubular secretion, has been shown to increase the plasma half-life of dyphylline.

Neutroxantina Contraindications

Hypersensitivity to dyphylline or related xanthine compounds.

Additional information about Neutroxantina

Neutroxantina Indication: For relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema.
Mechanism Of Action: The bronchodilatory action of dyphylline, as with other xanthines, is thought to be mediated through competitive inhibition of phosphodiesterase with a resulting increase in cyclic AMP producing relaxation of bronchial smooth muscle.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Dyphylline
Synonyms: Diprophylline; Dipropylline; Diprophyllin; Diprofilline; Diprofillin; Dihydroxypropyl Theopylin; Dihydroxypropyl Theophylline; DT
Drug Category: Vasodilator Agents; Bronchodilator Agents; Respiratory Smooth Muscle Relaxants; Phosphodiesterase Inhibitors
Drug Type: Small Molecule; Approved

Other Brand Names containing Dyphylline: Afi-Phyllin; Aristophyllin; Asthmolysin; Astrophyllin; Circain; Cor-Theophylline; Coronal; Coronarin; Corphyllin; Droxine; Dyflex; Glyfyllin; Glyphyllin; Glyphylline; Hidroxiteofillina; Hiphyllin; Hyphylline; Iphyllin; Liactemin; Neo-Vasophylline; Neophyl; Neophyllin; Neophylline; Neostenovasan; Neotilina; Neufil; Neutrafil; Neutrafillina; Neutraphyllin; Neutraphylline; Neutroxantina; Propyphyllin; Protheophylline; Purifilin; Silbephyllin; Silbephylline; Solufilin; Solufyllin; Soluphyllin; Synthophylline; Tefilan; Teofen; Theal; Thefylan;
Absorption: Not Available
Toxicity (Overdose): LD₅₀=1954 mg/kg (orally in mice)
Protein Binding: 84%
Biotransformation: Hepatic
Half Life: 2 hours (range 1.8 - 2.1 hours)
Dosage Forms of Neutroxantina: Tablet Oral
Chemical IUPAC Name: 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
Chemical Formula: C10H14N4O4
Dyphylline on Wikipedia: Not Available
Organisms Affected: Humans and other mammals