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Lycoremin: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Lycoremin - General Information

A benzazepine derived from norbelladine. It is found in galanthus and other amaryllidaceae. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of gallamine triethiodide and tubocurarine and has been studied as a treatment for alzheimer disease and other central nervous system disorders. [PubChem]

 

Pharmacology of Lycoremin

Lycoremin is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Lycoremin is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Lycoremin is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, Lycoremin's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that Lycoremin alters the course of the underlying dementing process.

 

Lycoremin for patients

Galantamine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Galantamine is in a class of medications called acetylcholinesterase inhibitors. It works by increasing the amount of a certain natural substance in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, galantamine will not cure AD or prevent the loss of mental abilities at some time in the future.

 

Lycoremin Interactions

 

Lycoremin Contraindications

REMINYL (galantamine hydrobromide) is contraindicated in patients with known hypersensitivity to galantamine hydrobromide or to any excipients used in the formulation.

 

Additional information about Lycoremin

Lycoremin Indication: For the treatment of mild to moderate dementia of the Alzheimer's type. Mechanism Of Action: Lycoremin's proposed mechanism of action involves the increase of the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Drug Interactions: Acepromazine Possible antagonism of actionAceprometazine Possible antagonism of actionAlverine Possible antagonism of actionAmantadine Possible antagonism of actionAmitriptyline Possible antagonism of actionAmoxapine Possible antagonism of actionAtropine Possible antagonism of actionAzatadine Possible antagonism of actionBelladona Possible antagonism of actionBenztropine Possible antagonism of actionBiperiden Possible antagonism of actionBrompheniramine Possible antagonism of actionCarbinoxamine Possible antagonism of actionChlorpheniramine Possible antagonism of actionChlorpromazine Possible antagonism of actionChlorprothixene Possible antagonism of actionCimetidine Possible antagonism of actionClemastine Possible antagonism of actionClidinium Possible antagonism of actionClomipramine Possible antagonism of actionClozapine Possible antagonism of actionCyclizine Possible antagonism of actionCyclobenzaprine Possible antagonism of actionCyproheptadine Possible antagonism of actionDarifenacin Possible antagonism of actionDesipramine Possible antagonism of actionDexbrompheniramine Possible antagonism of actionDicyclomine Possible antagonism of actionDimenhydrinate Possible antagonism of actionDiphenhydramine Possible antagonism of actionDiphenoxylate Possible antagonism of actionDiphenylpyraline Possible antagonism of actionDisopyramide Possible antagonism of actionDoxepin Possible antagonism of actionDoxylamine Possible antagonism of actionEthopropazine Possible antagonism of actionFlavoxate Possible antagonism of actionFlupenthixol Possible antagonism of actionGlutethimide Possible antagonism of actionGlycopyrrolate Possible antagonism of actionHydroxyzine Possible antagonism of actionHyoscyamine Possible antagonism of actionImipramine Possible antagonism of actionIsocarboxazid Possible antagonism of actionIsopropamide Possible antagonism of actionKetoconazole Ketoconazole increases the effect and toxicity of galantamineLoxapine Possible antagonism of actionMethotrimeprazine Possible antagonism of actionMaprotiline Possible antagonism of actionMeclizine Possible antagonism of actionMeperidine Possible antagonism of actionMesoridazine Possible antagonism of actionMethdilazine Possible antagonism of actionMirtazapine Possible antagonism of actionMethylscopolamine Possible antagonism of actionMoclobemide Possible antagonism of actionMolindone Possible antagonism of actionNortriptyline Possible antagonism of actionOlanzapine Possible antagonism of actionOrphenadrine Possible antagonism of actionOxybutynin Possible antagonism of actionPerphenazine Possible antagonism of actionPropericiazine Possible antagonism of actionParoxetine Paroxetine increases the effect and toxicity of galantaminePhenelzine Possible antagonism of actionPhenindamine Possible antagonism of actionPimozide Possible antagonism of actionPheniramine Possible antagonism of actionPipotiazine Possible antagonism of actionProcainamide Possible antagonism of actionProchlorperazine Possible antagonism of actionProcyclidine Possible antagonism of actionPromazine Possible antagonism of actionPromethazine Possible antagonism of actionPropantheline Possible antagonism of actionProtriptyline Possible antagonism of actionQuetiapine Possible antagonism of actionQuinidine Possible antagonism of actionQuinidine barbiturate Possible antagonism of actionRisperidone Possible antagonism of actionScopolamine Possible antagonism of actionSertraline Possible antagonism of actionSolifenacin Possible antagonism of actionThioproperazine Possible antagonism of actionThioridazine Possible antagonism of actionThiothixene Possible antagonism of actionTizanidine Possible antagonism of actionTolterodine Possible antagonism of actionTranylcypromine Possible antagonism of actionTrazodone Possible antagonism of actionTrifluoperazine Possible antagonism of actionTriflupromazine Possible antagonism of actionTrihexyphenidyl Possible antagonism of actionTrimeprazine Possible antagonism of actionTrimethobenzamide Possible antagonism of actionTrimipramine Possible antagonism of actionTripelennamine Possible antagonism of actionTriprolidine Possible antagonism of actionTrospium Possible antagonism of actionZiprasidone Possible antagonism of actionZuclopenthixol Possible antagonism of action Food Interactions: Take with food. Generic Name: Galantamine Synonyms: Galanthamine; Galanthamine hydrobromide; (-)-Galanthamine Drug Category: Nootropic Agents; Parasympathomimetics Drug Type: Small Molecule; Approved Other Brand Names containing Galantamine: Galantamin; Jilkon; Lycoremin; Lycoremine; Reminyl; Absorption: Not Available Toxicity (Overdose): LD50=75 mg/kg (rat) Protein Binding: 18% Biotransformation: Not Available Half Life: 7 hours Dosage Forms of Lycoremin: Tablet OralCapsule, extended release Oral Chemical IUPAC Name: (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol Chemical Formula: C17H21NO3 Galantamine on Wikipedia: https://en.wikipedia.org/wiki/Galantamine Organisms Affected: Humans and other mammals