HMS

HMS - General Information

HMS is a corticosteroid used in ophthalmology. [Wikipedia]

Pharmacology of HMS

HMS is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.

HMS for patients

HMS Interactions

No Informatuion Provided.

HMS Contraindications

HMS® (medrysone) is contraindicated in the following conditions:

Acute superficial herpes simplex

Viral diseases of the conjunctiva and cornea

Ocular tuberculosis

Fungal diseases of the eye

Hypersensitivity to any of the components of the drug

Additional information about HMS

HMS Indication: For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
Mechanism Of Action: There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Medrysone
Synonyms: Hydroxymesterone
Drug Category: Topical anti-inflammatory Agent
Drug Type: Small Molecule; Approved

Other Brand Names containing Medrysone: HMS Liquifilm; Medrifar; Medritonic; Medrocort; Visudrisone; HMS;
Absorption: Rapidly absorbed following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of HMS: Solution / drops Ophthalmic
Chemical IUPAC Name: (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Chemical Formula: C22H32O3
Medrysone on Wikipedia: https://en.wikipedia.org/wiki/Medrysone
Organisms Affected: Humans and other mammals