Enisyl
Enisyl - General Information
Enisyl (abbreviated as Lys or K)[1] is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG.
Enisyl is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Pharmacology of Enisyl
Insures the adequate absorption of calcium; helps form collagen (which makes up bone cartilage & connective tissues); aids in the production of antibodies, hormones & enzymes. Recent studies have shown that Lysine may be effective against herpes by improving the balance of nutrients that reduce viral growth. A deficiency may result in tiredness, inability to concentrate, irritability, bloodshot eyes, retarded growth, hair loss, anemia & reproductive problems.
Enisyl for patients
Pregnant women and nursing mothers should only consider using supplemental L-lysine if their diets are low in this amino acid. They should avoid supplemental L-lysine for other reasons. Proteins such as casein, which are high in L-lysine relative to L-arginine, are associated with elevated cholesterol levels. Those with hypercholesterolemia who are interested in taking supplemental L-lysine should be aware of this. Those with hepatic or renal failure should exercise caution in the use of supplemental L-lysine.
Enisyl Interactions
Concomitant use of calcium supplements and L-lysine may increase calcium absorption
Enisyl Contraindications
L-lysine supplementation is contraindicated in those with the rare genetic disorder hyperlysinemia/hyperlysinuria.
Additional information about Enisyl
Enisyl Indication: Supplemental L-lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Mechanism Of Action: Proteins of the herpes simplex virus are rich in L-arginine, and tissue culture studies indicate an enhancing effect on viral replication when the amino acid ratio of L-arginine to L-lysine is high in the tissue culture media. When the ratio of L-lysine to L-arginine is high, viral replication and the cytopathogenicity of herpes simplex virus have been found to be inhibited. L-lysine may facilitate the absorption of calcium from the small intestine.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: L-Lysine
Synonyms: 2,6-diaminohexanoic acid; L-lys; LYS; lysine; lysine acid
Drug Category: Dietary supplement; Micronutrient; Essential Amino Acids
Drug Type: Small Molecule; Nutraceutical; Approved
Other Brand Names containing L-Lysine: Enisyl;
Absorption: Absorbed from the lumen of the small intestine into the enterocytes by an active transport process
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic
Half Life: Not Available
Dosage Forms of Enisyl: Not Available
Chemical IUPAC Name: (2S)-2,6-diaminohexanoic acid
Chemical Formula: C6H14N2O2
L-Lysine on Wikipedia: https://en.wikipedia.org/wiki/L-Lysine
Organisms Affected: Humans and other mammals
