Dosing and uses of VoSoL HC (hydrocortisone/acetic acid otic)
Adult dosage forms and strengths
hydrocortisone/acetic acid/propylene glycol diacetate
otic solution
- 1%/ 2%/ 3%
Otitis Externa
Instill 3-5 gtt into affected ear 4-6 times/day
Pediatric dosage forms and strengths
hydrocortisone/acetic acid otic/propylene glycol diacetate
otic solution
- 1%/ 2%// 3%
Otitis Externa
<3 years
- Safety and efficacy not established
>3 years
- Instill 3-5 gtt into affected ear 4-6 times/day
Warnings
Contraindications
Hypersensitivity to drugs or components of the formulation; herpes simplex, varicella, vaccinia, perforated lymphatic membrane
Cautions
Use with extreme caution in patients < 3 years old; safety and efficacy not established
Pregnancy and lactation
Pregnancy category: C
Lactation: Low amounts excreted into breast milk; use with caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of VoSoL HC (hydrocortisone/acetic acid otic)
Mechanism of action
Hydrocortisone elicits anti-inflammatory & antipruritic effects
Acetic acid is used as an antibacterial/antifungal agent
