Dosing and uses of Vectical (calcitriol topical)
Adult dosage forms and strengths
ointment
- 0.0003%
Plaque Psoriasis
Apply to affected areas BId
200 mg/week maximum
Pediatric dosage forms and strengths
Safety & efficacy not established
Vectical (calcitriol topical) adverse (side) effects
>10%
Hypercalcemia (24%)
1-10%
Psoriasis (4%)
Pruritus (3%)
Skin discomfort (3%)
Urine abnormality (4%)
Warnings
Cautions
Avoid excessive sunlight
Absorbed in sufficient quantities to produce systemic effects
Pregnancy and lactation
Pregnancy category: C
Lactation: excretion in milk unknown; use with caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Vectical (calcitriol topical)
Absorption: yes
Mechanism of action
Vitamin D analog
