Dosing and uses of Tucks Hemorrhoidal Ointment (pramoxine/mineral oil/zinc oxide rectal)
Adult dosage forms and strengths
pramoxine/mineral oil/zinc oxide rectaL
topical ointment
- 1%/46.6%/12.5%
Topical Pain
For symptomatic relief of the discomfort associated with hemorrhoids, perianal itchin, or irritation
Apply externally to affected area up to 5 times daily PRn
Administration
When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly and gently dry by patting or blotting with toilet tissue or a soft cloth before application
Clean dispensing cap after every use
Pediatric dosage forms and strengths
pramoxine/mineral oil/zinc oxide rectaL
topical ointment
- 1%/46.6%/12.5%
Topical Pain
For symptomatic relief of the discomfort associated with hemorrhoids, perianal itching or irritation
<12 years: Safety and efficacy not established
≥12 years: Apply externally to affected area up to 5 times daily PRn
Administration
When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly and gently dry by patting or blotting with toilet tissue or a soft cloth before application
Clean dispensing cap after every use
Tucks Hemorrhoidal Ointment (pramoxine/mineral oil/zinc oxide rectal) adverse (side) effects
Frequency not defined
Irritation
Pruritus
Warnings
Contraindications
Hypersensitivity
Cautions
For external use only
Do not use in the eyes
Do not use on blistered or broken skin
If condition worsens, or if symptoms persist for >7 days or clear up and occur again within a few days, discontinue and reassess therapy
Pregnancy and lactation
Pregnancy category: Undetermined, caution advised
Lactation: Unknown if excreted in breast milk, caution advised
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Tucks Hemorrhoidal Ointment (pramoxine/mineral oil/zinc oxide rectal)
Mechanism of action
Pramoxine: local anesthetic due to inhibition of conduction of nerve impulses from sensory nerves, resulting from an alteration of the cell membrane permeability to ions
Zinc oxide: antiseptic and protectant properties
Absorption
MinimaL
Onset: 3-5 min
