Dosing and uses of Tri-Chlor (trichloroacetic acid topical)
Adult dosage forms and strengths
topical liquid
- 80%
Condylomata
Protect skin surrounding lesion with petrolatum; then apply topically to lesion and cover with dressing for ~5 days
Pediatric dosage forms and strengths
Safety and efficacy not established
Tri-Chlor (trichloroacetic acid topical) adverse (side) effects
Frequency not defined
Skin toxicity (severe burning, inflammation, or tenderness)
Warnings
Contraindications
Hypersensitivity
Malignant or premalignant lesions
Cautions
Apply externally by physician (not for self-use)
Thoroughly diagnose cervical lesion to rule out malignancy; contraindicated for malignant or premalignant lesions
If accidentally applied to healthy tissue, remove immediately and wash area with warm water; sodium bicarbonate may be used as local antidote
Pregnancy and lactation
Pregnancy category: C
Lactation: Unknown whether distributed in breast milk, caution advised
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Tri-Chlor (trichloroacetic acid topical)
Mechanism of action
Keratolytic; induces desquamation when applied to cornified epithelium
