carboxymethylcellulose ophthalmic (TheraTears Nighttime Dry Eye Therapy, Refresh Optive Gel Drops)

Dosing and uses of TheraTears Nighttime Dry Eye Therapy, Refresh Optive Gel Drops (carboxymethylcellulose ophthalmic)

• Adult
• Pediatric

 

Adult dosage forms and strengths

ophthalmic gel drops

• 1% single-unit containers (TheraTears Nighttime Dry Eye Therapy)
• 1% 10mL bottle; other ingredient: glycerin 0.9% (Refresh Optive Gel Drops)

 

Dry Eyes

Instill 1-2 gtt in affected eye(s) prn

Indications

• Lubricant to relieve dry eyes
• Protectant against further eye irritation
• Temporary relief of burning, irritation and discomfort including exposure to wind or sun

 

Pediatric dosage forms and strengths

Safety and efficacy not established

 

TheraTears Nighttime Dry Eye Therapy, Refresh Optive Gel Drops (carboxymethylcellulose ophthalmic) adverse (side) effects

None listed on manufacturer's labeling

 

Warnings

Contraindications

Hypersensitivity to ingredients

 

Cautions

For topical ophthalmic use only

Reuse of single-use product may lead to ophthalmic inflammation and/or discomfort, based on potential contamination during handling

Discontinue and contact physician if pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for >72 hr

 

Pregnancy and lactation

 

Pregnancy

No information; unlikely to be absorbed systemically

 

Lactation

Unknown if distributed in human breast milk; unlikely to be absorbed systemically

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of TheraTears Nighttime Dry Eye Therapy, Refresh Optive Gel Drops (carboxymethylcellulose ophthalmic)

Mechanism of action

Ophthalmic lubricant

 

Administration

Ophthalmic Administration

Do not touch tip to eye (avoid touch contamination)

Do no use if gel changes color or becomes cloudy

TheraTears Nighttime Dry Eye Therapy

• To open, twist tab completely off
• For single-use only; contains no preservatives
• Do not reuse; once open, discard
• Use individual vials within 90 days of opening foil pouch