Quercetin
Classes: Cardiovascular, Herbals; Ear, Eye, Nose & Throat, Herbals; Oncology, Herbals; Urology, Herbals
Suggested dosing of Quercetin
400-500 mg PO TId
Prostatitis: 500 mg PO BId
Cancer: 420-1400 mg/sq.meter IV bolus qWeek
Suggested uses of Quercetin
Seasonal allergy; prevention of diabetic cataracts; viral infections; CVd
Adjunctive therapy in cancer
Chronic prostatitis, interstitial cystitis
Efficacy
Possibly effective in treatment of nonbacterial chronic prostatitis, interstitial cystitis
Other uses mainly derived from animal studies
Quercetin adverse (side) effects
Frequency not defined
PO: Headache
PO: Paresthesia
IV: Dyspnea
IV: N/V
IV: Nephrotoxicity (>945 mg/sq. meter)
Warnings
Contraindications
Sophretin, meletin
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Quercetin
Metabolism: N/A
Excretion: N/A
Mechanism of action
Flavonoid found in many foods; anti-inflammatory, antioxidant
Inhibits aldose reductase in lens