magnesium salicylate/pamabrom (Pamprin Maximum Pain Relief Caplets)
Classes: Analgesics, Other Combos
Dosing and uses of Pamprin Maximum Pain Relief Caplets (magnesium salicylate/pamabrom)
Dosing Forms & Strength
magnesium salicylate/pamabrom
tablet
- 250mg/25mg
Analgesia/Menstrual Cramps
1-2 tablets PO q4-6hr PRn
Pediatric dosage forms and strengths
Safety & efficacy not established
Pamprin Maximum Pain Relief Caplets (magnesium salicylate/pamabrom) adverse (side) effects
Frequency not defined (common)
Tinnitus (high or chronic dose)
Rash
Urticaria
Dyspepsia
Heartburn
Nausea
Vomiting
Stomach pain
Warnings
Contraindications
Hypersensitivity
Repeated administration in patients with anemia, pulmonary, cardiac conditions, or renal disease
Cautions
Gastrointestinal bleeding; particular caution in patients with history of GI bleed, alcoholism, or bleeding disorders
Avoid with active peptic ulcer disease, severe hepatic impairment, and severe renal impairment (ie, CrCl<10 mL/min)
Pregnancy and lactation
Pregnancy category: D; avoid during pregnancy, particularly in third trimester because of risk for premature closure of the ductus arteriosus
Lactation: Excreted in breast milk; not recommended
Seek advice of health professional before using OTC drugs if pregnant or breastfeeding
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Pamprin Maximum Pain Relief Caplets (magnesium salicylate/pamabrom)
Mechanism of action
Magnesium salicylate: Nonsteroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic properties.
Pamabrom: Weak diuretic action
