Dosing and uses of Oxilan (ioxilan)
Adult dosage forms and strengths
injectable solution
- 300mgI/mL
- 350mgI/mL
IV Administration
CECT of Head
- Oxilan 300: 100-200 mL
- Oxilan 350: 86-172 mL
- Not to exceed 200 mL
CECT of Body
- Oxilan 300: 50-200 mL
- Oxilan 350: 43-172 mL
- Not to exceed 200 mL
Intraarterial Administration
Coronary Arteries: 2-10 mL Oxilan 350
LV: 25-50 mL Oxilan 350
Other Information
For other uses see Mfr's PI
Other Indications & Uses
CECT of head & body; arteriography; ventriculography; IV excretory urography
Pediatric dosage forms and strengths
Safety & efficacy not established
Warnings
Contraindications
Intrathecal administration (potentially fatal)
Cautions
Severe renal impairment, combined renal/hepatic disease, severe thyrotoxicosis, myelomatosis, anuria, pheochromocytoma, sickle cell, CHF, severe arterial/venous disease
May cause renal failure in pts w/ advanced vascular disease, diabetes; should be well hydrated before/after procedure
Hypersensitivity to contrast medium, iodine
Inhibits blood coagulation (less than ionic contrast media in vitro)
Allergies (bronchial asthma, hay fever, food allergies)
Pregnancy and lactation
Pregnancy category: B
Lactation: not known, use caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Oxilan (ioxilan)
Distribution: mainly blood
Excretion: urine