xylometazoline (Triaminic Decongestant Spray Nasal and Sinus Congestion)

Dosing and uses of Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline)

• Adult
• Pediatric

 

Adult dosage forms and strengths

nasal drops/spray

• 0.05%
• 0.1%

 

Nasal Congestion

0.1% Spray (>12 years old): 2-3 gtt/sprays per nostril q8-10hours, no more than 3 doses/day

 

Pediatric dosage forms and strengths

nasal drops/spray

• 0.05%
• 0.1%

 

Nasal Congestion

0.05% Spray (2-12 years old): 2-3 gtt per nostril q8-10hours, MAXIMUM 3 doses/24 hours

0.1% Spray (>12 years old): 2-3 gtt/sprays per nostril q8-10hours, no more than 3 doses/day

 

Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline) adverse (side) effects

Frequency not defined

Anxiety

Dizzy

Tremor

Overuse may cause rebound congestion

Topical products may cause local side effects such as burning, stinging, dryness

 

Warnings

Contraindications

Heart disease (incr BP, HR, palpitations)

MAOIs

 

Pregnancy and lactation

Pregnancy category: C

Lactation: not known if excreted in breast milk

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline)

Onset: 5-10 min

Duration: 5-6 hr

Metabolism: unknown

Excretion: unknown

 

Mechanism of action

Alpha adrenergic agonist