Suggested dosing of Octacosyl alcohol (octacosanol)
Exercise Endurance
1 mg PO qDay
Cholesterol Lowering
10-20 mg PO qDay
Parkinson's Disease
5 mg PO TID with meals
Amytrophic Lateral Sclerosis (ALS)
40 mg PO qDay
Suggested uses of Octacosyl alcohol (octacosanol)
Enhance physical endurance
Lower cholesterol & increase HDL
Parkinson's Disease
ALs
Efficacy
Small clinical studies suggest some benefit regarding endurance & Parkinson's Disease
Octacosyl alcohol (octacosanol) adverse (side) effects
None reported
Warnings
None
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Octacosyl alcohol (octacosanol)
Absorption: low
Metabolism: N/A
Excretion: feces, metabolites in urine
Mechanism of action
Long chain aliphatic alcohol; may improve oxygen utilization by muscle cells, lower lactic acid accumulation during exercise
