naphazoline/pheniramine ophthalmic (Naphcon-A, Opcon-A, Visine-A)
Dosing and uses of Naphcon-A, Opcon-A (naphazoline/pheniramine ophthalmic)
Adult dosage forms and strengths
naphazoline/pheniramine
ophthalmic solution
- 0.025%/0.3%
- 0.027%/0.3%
Allergic Conjunctivitis
Instill 1-2 drops in affected eye(s) up to 4 times daily
Other Information
Remove contact lenses before using
Store at room temp; protect from light and excessive heat; use before expiration date
Pediatric dosage forms and strengths
naphazoline/pheniramine
ophthalmic solution
- 0.025%/0.3%
- 0.027%/0.3%
Allergic Conjunctivitis
<6 years: Not established
6 years or older: 1-2 drops in affected eye(s) up to 4 times daily
Other Information
Remove contact lenses before using
Store at room temp; protect from light and excessive heat; use before expiration date
Naphcon-A, Opcon-A (naphazoline/pheniramine ophthalmic) adverse (side) effects
Frequency not defined
Stinging/tingling sensation upon instillation
Mydriasis
Ocular erythema
Warnings
Contraindications
Hypersensitivity
Cautions
Cardiac disease
Hypertension
Benign prostatic hypertrophy
Narrow angle glaucoma
Pregnancy and lactation
Pregnancy category: C
Lactation: Unknown whether distributed in breast milk, weigh benefits against risks
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Naphcon-A, Opcon-A (naphazoline/pheniramine ophthalmic)
Absorption: Negligible systemic absorption
Mechanism of action
Naphazoline: alpha-adrenergic agonist (decongestant)
Pheniramine: H1 blocker (antihistamine)
