triamcinolone/nystatin (MyCo-Triacet II, Mycolog II, Mycogen II, Mytrex, Tri-Statin II)
Classes: Antifungal/Corticosteroid Topicals
Dosing and uses of MyCo-Triacet II, Mycolog II (triamcinolone/nystatin)
Adult dosage forms and strengths
triamcinolone/nystatin
topical cream/ointment
- (0.1%/100,000units)/g
Cutaneous Candidiasis
Apply cream / ointment BId
Pediatric dosage forms and strengths
triamcinolone/nystatin
topical cream/ointment
- (0.1%/100,000units)/g
Cutaneous Candidiasis
As adults; apply cream / ointment BId
MyCo-Triacet II, Mycolog II (triamcinolone/nystatin) adverse (side) effects
Frequency not defined
Blistering
Burning
Dryness
Acniform eruptions
Excessive discoloring of the skin
Excessive hair growth (especially on face)
Hair loss (especially on scalp)
Inflammation around the mouth
Inflammation of hair follicles
Irritation
Itching
Peeling
Prickly heat
Striae
Secondary infection
Skin inflammation
Softening of the skin
Stretch marks
Stretching or thinning of the skin
Warnings
Contraindications
Hypersensitivity
Cautions
For topical use only
Not for ophthalmic use
Risk of HPA axis suppression with corticosteroids when used on large body surface area, with prolonged use, or with occlusive dressings
Pregnancy and lactation
Pregnancy category: unknown
Lactation: unknown if excreted in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of MyCo-Triacet II, Mycolog II (triamcinolone/nystatin)
Triamcinolone potency
Medium
Very-high: clobetasol, diflorasone diacetate ointment 0.05%, halobetasoL
High: betamethasone dipropionate 0.05%, amcinonide, fluocinonide, desoximetasone, mometasone, diflorasone emollient 0.05%, halcinonide
Medium: triamcinolone, betamethasone valerate 0.1%, fluticasone, flurandrenolide, fluocinolone 0.025%, hydrocortisone
Mild: hydrocortisone 0.5, 1, 2.5% base, desonide, alclometasone
Mechanism of action
Nystatin: Antifungal activity
Triamcinolone: Corticosteroid; elicits antipruritic and anti-inflammatory effects
