triamcinolone/nystatin (MyCo-Triacet II, Mycolog II, Mycogen II, Mytrex, Tri-Statin II)

Dosing and uses of MyCo-Triacet II, Mycolog II (triamcinolone/nystatin)

• Adult
• Pediatric

 

Adult dosage forms and strengths

triamcinolone/nystatin

topical cream/ointment

• (0.1%/100,000units)/g

 

Cutaneous Candidiasis

Apply cream / ointment BId

 

Pediatric dosage forms and strengths

triamcinolone/nystatin

topical cream/ointment

• (0.1%/100,000units)/g

 

Cutaneous Candidiasis

As adults; apply cream / ointment BId

 

MyCo-Triacet II, Mycolog II (triamcinolone/nystatin) adverse (side) effects

Frequency not defined

Blistering

Burning

Dryness

Acniform eruptions

Excessive discoloring of the skin

Excessive hair growth (especially on face)

Hair loss (especially on scalp)

Inflammation around the mouth

Inflammation of hair follicles

Irritation

Itching

Peeling

Prickly heat

Striae

Secondary infection

Skin inflammation

Softening of the skin

Stretch marks

Stretching or thinning of the skin

 

Warnings

Contraindications

Hypersensitivity

 

Cautions

For topical use only

Not for ophthalmic use

Risk of HPA axis suppression with corticosteroids when used on large body surface area, with prolonged use, or with occlusive dressings

 

Pregnancy and lactation

Pregnancy category: unknown

Lactation: unknown if excreted in breast milk

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of MyCo-Triacet II, Mycolog II (triamcinolone/nystatin)

Triamcinolone potency

Medium

Very-high: clobetasol, diflorasone diacetate ointment 0.05%, halobetasoL

High: betamethasone dipropionate 0.05%, amcinonide, fluocinonide, desoximetasone, mometasone, diflorasone emollient 0.05%, halcinonide

Medium: triamcinolone, betamethasone valerate 0.1%, fluticasone, flurandrenolide, fluocinolone 0.025%, hydrocortisone

Mild: hydrocortisone 0.5, 1, 2.5% base, desonide, alclometasone

 

Mechanism of action

Nystatin: Antifungal activity

Triamcinolone: Corticosteroid; elicits antipruritic and anti-inflammatory effects