Dosing and uses of Mentax ([Lotrimin Ultra] terbutaline)
Adult dosage forms and strengths
cream
- 1%
Tinea Pedis
Cream: Apply to affected areas BID for at least 1 week; not to exceed 4 weeks
Gel: Apply to affected area BID for 7 days
Solution: Apply to affected area BID for 7 days
Ringworm & Jock Itch (Tinea Corporis, Tinea Cruris)
Cream: Apply to affected area qDay/BID for at least 1 week; not to exceed 4 weeks
Gel: Apply to affected area once daily for 7 days
Solution: Apply to affected area qDay for 7 days in tinea corporis and tinea cruris; apply to affected areas BID for 7 days in tinea versicolor
Tinea (Pityriasis) Versicolor
Apply qDay for 2 weeks
Pediatric dosage forms and strengths
cream
- 1%
Tinea Pedis
<12 years old: Safety & efficacy not established
>12 years old: As in adults
Ringworm & Jock Itch (Tinea Corporis, Tinea Cruris)
<12 years old: Safety & efficacy not established
>12 years old: As in adults
Mentax ([Lotrimin Ultra] terbutaline) adverse (side) effects
Common
burning
stinging
Less Common
contact dermatitis
erythema
irritation
itching
Warnings
Contraindications
Hypersensitivity
Pregnancy and lactation
Pregnancy category: C
Lactation: excretion in milk unknown; use with caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Mentax ([Lotrimin Ultra] terbutaline)
Peak Plasma Time: 8-15 hr
Metabolism: liver
Excretion: urine
Mechanism of action
Synthetic benzylamine topical antifungal similar to allylamines (terbinafine, naftifine) that inhibits intermediary in synthesis of ergosterol, an essential component of fungal cell membranes
Fungistatic
