Suggested dosing of La Pacho, Tabebuia avellanedae (pau d'arco)
1-4 g/d div BID-TID, use not more than 7d
1 tsp bark steeped in boiling water, 2-8 x/day
Dose based on lapachol content; lapachol intake should be 1.5-2.0 g/day
Suggested uses of La Pacho, Tabebuia avellanedae (pau d'arco)
Antimicrobial, especially anti-Candida
Claimed to be anti-cancer
Efficacy
Insufficient reliable data available
La Pacho, Tabebuia avellanedae (pau d'arco) adverse (side) effects
Frequency not defined
Nausea
Vomiting
Dizziness
Anti-coagulant effects (reduced by using whole bark)
Warnings
Contraindications
N/A
Cautions
Products highly variable in lapachol content
Negative anti-cancer results found by NCI based on isolated lapachol; whole bark contains synergistic compounds that reduce ADR's
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of La Pacho, Tabebuia avellanedae (pau d'arco)
Metabolism: N/A
Excretion: N/A
Mechanism of action
AntimicrobiaL
