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cadexomer iodine (Iodosorb)

 

Classes: Wound Care

Dosing and uses of Iodosorb (cadexomer iodine)

 

Adult dosage forms and strengths

geL

  • 0.9% iodine

 

Antibacterial & Absorbent Agent

Spread in1/8-1/4 inch to dry sterile gauze; apply gauze on wound

No more than 50 g per application; no more than 150 g/week

Change 3 times per week or when color turns to yellow/gray

 

Other Indications & Uses

Cleaning wet ulcers & wounds; reduces microbial load including MRSA, absorbs exudate, helps in debridement, creates moist wound environment, & retards eschar formation

 

Pediatric dosage forms and strengths

Safety & efficacy not established

 

Iodosorb (cadexomer iodine) adverse (side) effects

Frequency not defined

Transient slight/moderate pain

Redness or swelling at application site

 

Warnings

Contraindications

Iodine sensitivity

Hashimoto's thyroiditis, history of Graves dz or nontoxic goiter

Pregnancy, lactation

Dry wounds

 

Cautions

Limit use of a tube to one pt.

NMT 3 mth

 

Pregnancy and lactation

Pregnancy category: do not use

Lactation: do not nurse

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Iodosorb (cadexomer iodine)

Metabolism: N/A

Excretion: N/A

 

Mechanism of action

Releases iodine that has antimicrobial function