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Boswellia (Indian frankincense)

 

Classes: Gastrointestinal, Herbals; Musculoskeletal, Herbals

Suggested dosing of Indian frankincense (boswellia)

Follow Mfr's instructions

 

General Dosing Guidelines

300-500 mg PO BID/TId

 

Osteoarthritis

Extract: 333 mg TID PO

 

Rheumatoid Arthritis

Extract: 3600 mg/day

 

Ulcerative Colitis

Gum Resin preparation: 350 mg TID PO

 

Bronchial Asthma

300 mg TID PO

Generally 300-500 mg PO BID/TID, higher in IBd

 

Suggested uses of Indian frankincense (boswellia)

Osteoarthritis, rheumatoid arthritis, asthma, inflammatory bowel disease, diuretic, painful menstration

 

Efficacy

Clinical trials have shown beneficial evidence for all of the above uses but of varying consistency & reliability

 

Indian frankincense (boswellia) adverse (side) effects

Frequency not defined

Diarrhea

Nausea etc

 

Warnings

Contraindications

Pregnancy

 

Cautions

May be emmenagogue & abortificient

 

Pregnancy and lactation

Pregnancy category: avoid

Lactation: N/A

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Indian frankincense (boswellia)

Metabolism: N/A

Excretion: N/A

 

Mechanism of action

Boswellic acid, the major constituent is thought to contain pharmacologic potency

Inhibits 5-lipoxygenase in vitro & in animal studies

Antiinflammatory