Navigation

gentamicin topical (Garamycin topical)

 

Classes: Antibacterials, Topical

Dosing and uses of Garamycin topical (gentamicin topical)

 

Adult dosage forms and strengths

cream/ointment

  • 1%

 

Gram-Negative Infections

Topical: Apply to affected area TID-QId

See also combo with betamethasone (Cdn)

 

Pediatric dosage forms and strengths

cream/ointment

  • 1%

 

Gram-Negative Infections

> 1yo: Topical: Apply to affected area TID-QId

 

Garamycin topical (gentamicin topical) adverse (side) effects

Frequency not defined

Allergic contact dermatitis

Erythema

Pruritus

 

Warnings

Contraindications

Hypersensitivity

Skin rash

 

Pregnancy and lactation

Pregnancy category: C

Lactation: excreted in breast milk; no adverse effect on nursing infant

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Garamycin topical (gentamicin topical)

Absorption: no

 

Mechanism of action

Bactericidal; appears to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S ribosomal subunits