Dosing and uses of Garamycin topical (gentamicin topical)
Adult dosage forms and strengths
cream/ointment
- 1%
Gram-Negative Infections
Topical: Apply to affected area TID-QId
See also combo with betamethasone (Cdn)
Pediatric dosage forms and strengths
cream/ointment
- 1%
Gram-Negative Infections
> 1yo: Topical: Apply to affected area TID-QId
Garamycin topical (gentamicin topical) adverse (side) effects
Frequency not defined
Allergic contact dermatitis
Erythema
Pruritus
Warnings
Contraindications
Hypersensitivity
Skin rash
Pregnancy and lactation
Pregnancy category: C
Lactation: excreted in breast milk; no adverse effect on nursing infant
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Garamycin topical (gentamicin topical)
Absorption: no
Mechanism of action
Bactericidal; appears to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S ribosomal subunits