aluminum hydroxide/magnesium trisilicate (Gaviscon Regular Strength Tablets)
Classes: Antacids, Combos
- Dosing and uses of Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate)
- Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate) adverse (side) effects
- Warnings
- Pregnancy
- Pharmacology of Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate)
Dosing and uses of Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate)
Adult dosage forms and strengths
aluminum hydroxide/magnesium trisilicate
tablet, chewable
- 80mg/14.2mg
Gastric Hyperacidity, Heartburn
Regular Strength Tablets: Chew 2-4 tablets PO QID prn; not to exceed 16 tablets/day
Other Indications & Uses
Off-label: Peptic ulcer disease, GERd
Pediatric dosage forms and strengths
<12 years: Not recommended
Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate) adverse (side) effects
>10%
Aluminum
- Chalky taste
- Constipation
- Fecal impaction
- Stomach cramps
1-10%
Aluminum
- Nausea
- Vomiting
- Aluminum intoxication
- Hypophosphatemia
- Osteomalacia
Magnesium
- Diarrhea
- Hypermagnesemia
Warnings
Contraindications
Hypersensitivity
Cautions
Renal failure
Magnesium restricted diet
May increase or decrease rate and/or degree of absorption of concomitantly administered oral drugs by changing GI transit time, pH, or by cationic binding
Pregnancy and lactation
Pregnancy category: C
Lactation: Unknown whether distributed in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Gaviscon Regular Strength Tablets (aluminum hydroxide/magnesium trisilicate)
Duration: 2-60 min (fasting); up to 3 hr (1 hr pc)
Excretion
Feces: 95% aluminium ions; 70% magnesium ions
Urine: 5% aluminum ions; up to 30% magnesium ions
Mechanism of action
Neutralizes gastric acidity by increasing gastric pH