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castor oil (Fleet Castor Oil, Emulsoil)

 

Classes: Laxatives, Other

Dosing and uses of Fleet Castor Oil (castor oil)

 

Adult dosage forms and strengths

oral solution

  • 30mL
  • 60mL

 

Constipation

15 ml PO x1

 

Colonic Evacuation

15-60 ml PO x1, 16 hours before procedure

 

Other Indications & Uses

Usually reserved for total colonic evacuation before GI procedure

 

Pediatric dosage forms and strengths

oral solution

  • 30mL
  • 60mL

 

Constipation

<2 years old: 1-5 mL PO once

2-12 years old: 5-15 mL PO once

>12 years old: As in adults

 

Fleet Castor Oil (castor oil) adverse (side) effects

Frequency not defined

Excessive bowel activity

Abdominal cramping

Yellow/brown urine discoloration

Laxative dependence (Avoid chronic use)

 

Warnings

Contraindications

Hypersensitivity, GI obstruction or perforation, severe impaction, symptoms of appendicitis or acute surgical abdomen, ulcerative colitis, rectal fissures

Avoid in pregnancy: can induce premature labor

 

Pregnancy and lactation

Pregnancy category: X

Lactation: safe

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Fleet Castor Oil (castor oil)

Onset: 2-6 hr

 

Mechanism of action

Irritant/stimulant laxative