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Evening Primrose Oil (fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop)

 

Classes: Cardiovascular, Herbals

Suggested dosing of Fever plant, kings cureall (evening primrose oil)

 

Eczema, Atopic

4-6 g PO daily

 

Mastalgia

3-4 g PO daily

 

Premenstrual Syndrome

2-4 g PO daily

 

Rheumatoid Arthritis

540 mg-2.8 g PO daily

 

Suggested uses of Fever plant, kings cureall (evening primrose oil)

CAD, eczema (atopic), endometriosis, GI disorders, hypercholesterolemia, intermittent claudication, mastalgia, menopausal symptoms, osteoporosis, premenstrual syndrome, rheumatoid arthritis

 

Efficacy

Possibly effective for PMS, mastalgia, osteoporosis

 

Fever plant, kings cureall (evening primrose oil) adverse (side) effects

Frequency not defined

Headache

Indigestion

Nausea

Pregnancy complications

Soft stools

 

Warnings

Contraindications

None Reported

 

Cautions

Bleeding disorders, concomitant anesthesia, schizophrenia, seizure disorder

 

Pregnancy and lactation

Pregnancy category: X

Lactation: unsafe

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Fever plant, kings cureall (evening primrose oil)

Metabolism: N/A

Excretion: N/A

 

Mechanism of action

Gamma-linolenic acid (GLA) metabolized to anti-inflammatory prostaglandins