Evening Primrose Oil (fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop)
Classes: Cardiovascular, Herbals
Suggested dosing of Fever plant, kings cureall (evening primrose oil)
Eczema, Atopic
4-6 g PO daily
Mastalgia
3-4 g PO daily
Premenstrual Syndrome
2-4 g PO daily
Rheumatoid Arthritis
540 mg-2.8 g PO daily
Suggested uses of Fever plant, kings cureall (evening primrose oil)
CAD, eczema (atopic), endometriosis, GI disorders, hypercholesterolemia, intermittent claudication, mastalgia, menopausal symptoms, osteoporosis, premenstrual syndrome, rheumatoid arthritis
Efficacy
Possibly effective for PMS, mastalgia, osteoporosis
Fever plant, kings cureall (evening primrose oil) adverse (side) effects
Frequency not defined
Headache
Indigestion
Nausea
Pregnancy complications
Soft stools
Warnings
Contraindications
None Reported
Cautions
Bleeding disorders, concomitant anesthesia, schizophrenia, seizure disorder
Pregnancy and lactation
Pregnancy category: X
Lactation: unsafe
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Fever plant, kings cureall (evening primrose oil)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Gamma-linolenic acid (GLA) metabolized to anti-inflammatory prostaglandins