Dosing and uses of Ertaczo (sertaconazole)
Adult dosage forms and strengths
cream
- 2%
Tinea Pedis
Apply BID x 4 weeks; apply enough to cover affected area, & immediately surrounding healthy skin
If no improvement 2 weeks after treatment period, review diagnosis
Other Indications & Uses
Interdigital tinea pedis in immunocompetent patients >12 years old:, caused by Tricophyton rubrum, Tricophyton mentagrophytes, & Epidermophyton floccosum
Pediatric dosage forms and strengths
<12 years old: Safety & efficacy not established
Ertaczo (sertaconazole) adverse (side) effects
Frequency not defined
Contact dermatitis
Dry skin
Burning
Erythema
Vesiculation
Desquamation
Hyperpigmentation
Warnings
Contraindications
Hypersensitivity
Not indicated for ophthalmic, oral or intravaginal use
Cautions
Sensitivity to imidazole antifungals (cross-reactivity may occur)
Pregnancy and lactation
Pregnancy category: C
Lactation: not known if distributed into milk; use caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Ertaczo (sertaconazole)
Absorption: minimaL
Mechanism of action
Imidazole class of antifungals; believed to inhibit cytochrome P450-dependent synthesis of ergosterol, leading to fungal cell membrane injury through leakage of key constituents
