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mometasone topical (Elocon)

 

Classes: Corticosteroids, Topical

Dosing and uses of Elocon (mometasone topical)

 

Adult dosage forms and strengths

cream/lotion/ointment

  • 0.1%

 

Inflammatory Hyperkeratotic Dermatosis

Apply cream, lotion or ointment to affected area qDay

 

Administration

Do not use with occlusive dressings

 

Other Indications & Uses

Dermatosis-associated inflammation and pruritus

Potency: Medium

 

Pediatric dosage forms and strengths

cream/lotion/ointment

  • 0.1%

 

Inflammatory Hyperkeratotic Dermatosis

<2 years: Safety and efficacy not established

2 years or older: As adults: apply cream, lotion or ointment to affected area qDay

Use beyond 3 weeks not studied

 

Elocon (mometasone topical) adverse (side) effects

Frequency not defined

Burning

Itching

Pruritus

Rosacea

 

Warnings

Contraindications

Hypersensitivity

 

Cautions

Safety/efficacy in children use for longer than 3 wk not established

Potential for HPA axis suppression

Do not use with occlusive dressings

Not for acne, rosacea, perioral dermatitis, diaper dermatitis

 

Pregnancy and lactation

Pregnancy category: C

Lactation: use caution

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Elocon (mometasone topical)

Absorption: 0.4%

Metabolism: hepatic P450 enzyme CYP3A4

Excretion: N/A

 

Potency

Medium

Relative potency: ointment >cream >lotion >solution

Very-high: clobetasol, diflorasone diacetate ointment 0.05%, halobetasoL

High: betamethasone dipropionate 0.05%, amcinonide, fluocinonide, desoximetasone, mometasone, diflorasone emollient 0.05%, halcinonide

Medium: triamcinolone, betamethasone valerate 0.1%, fluticasone, flurandrenolide, fluocinolone 0.025%, hydrocortisone

Mild: hydrocortisone 0.5, 1, 2.5% base, desonide, alclometasone

 

Mechanism of action

Anti-inflammatory corticosteroid