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Medically reviewed by Min Clinic Staff | Updated: January 2026
Dosing and uses of Austedo (deutetrabenazine)
Huntington Disease
Pending FDA approval for treatment of chorea associated with Huntington disease
Pharmacology of Austedo (deutetrabenazine)
Mechanism of action
Oral vesicular monoamine transporter-2 (VMAT-2) inhibitor, resulting in decreased uptake of monoamines (eg, dopamine, serotonin, norepinephrine, histamine) into synaptic vesicles and depletion of monoamine stores from nerve terminals