Dosing and uses of Dermabond (2-octyl cyanoacrylate)
Adult dosage forms and strengths
prefilled applicator
- topical liquid adhesive available in boxes of 6 or 12
Topical Skin Adhesive
Indicated for topical application to hold closed easily approximated skin edges of wounds
May be used for surgical incisions (including punctures from minimally invasive surgery) and trauma-induced lacerations, not under tension, that are simple and thoroughly cleansed
May be used with, but not in place of, deep dermal stitches
Apply in multiple thin layers to approximated wound edges, with wound in horizontal position
Pediatric dosage forms and strengths
prefilled applicator
- topical liquid adhesive available in boxes of 6 or 12
Topical Skin Adhesive
Indicated for topical application to hold closed easily approximated skin edges of wounds
May be used for surgical incisions (including punctures from minimally invasive surgery) and trauma-induced lacerations, not under tension, that are simple and thoroughly cleansed
May be used with, but not in place of, deep dermal stitches
Apply in multiple thin layers to approximated wound edges, with wound in horizontal position
Dermabond (2-octyl cyanoacrylate) adverse (side) effects
>10%
Erythema (11.5%)
1-10%
Dehiscence with need for retreatment (2.5%)
Edema (9.7%)
Pain (6.1%)
Suspected infection (3.6%)
Warmth (1.3%)
Warnings
Contraindications
Wounds with active infection, gangrene, or of decubitus etiology
Use on eye, mucosal surfaces, skin exposed to body fluids, or skin with dense hair
Hypersensitivity to cyanoacrylate or formaldehyde
Cautions
Use only on wounds that have been cleaned & debrided; do not use on moist wounds
Do not use on high-tension areas (knuckles, elbows, etc)
Pregnancy and lactation
Pregnancy category: no studies found
Lactation: no studies found
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Dermabond (2-octyl cyanoacrylate)
Mechanism of action
Liquid polymerizes to form adhesive
