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bacitracin and lidocaine topical (CVS Bacitracin With Pain Relief)

 

Classes: Anesthetics, Topical; Antibacterials, Topical

Dosing and uses of CVS Bacitracin With Pain Relief (bacitracin and lidocaine topical)

 

Adult dosage forms and strengths

bacitracin/lidocaine

ointment

  • (500 units/4%)/g

 

Minor Cuts, Scrapes & Burns

Indicated to prevent infection and temporarily relieve pain in minor cuts, scrapes, and burns

After cleaning affected area, apply small amount topically 1-3 times/day; cover with sterile bandage

 

Pediatric dosage forms and strengths

bacitracin/lidocaine

ointment

  • (500 units/4%)/g

 

Minor Cuts, Scrapes & Burns

Indicated to prevent infection and temporarily relieve pain in minor cuts, scrapes, and burns

<2 years: Safety and efficacy not established

≥2 years: After cleaning affected area, apply small amount topically 1-3 times/day; cover with sterile bandage

 

CVS Bacitracin With Pain Relief (bacitracin and lidocaine topical) adverse (side) effects

Frequency not defined

Rash

Hypersensitivity (rare)

 

Warnings

Contraindications

Hypersensitivity to bacitracin, lidocaine, or other anesthetic amides (eg, bupivacaine)

 

Cautions

For external use only

Avoid contact with eyes

Do not use over large areas of body

Not for deep puncture wound, animal bites, or serious burns

Discontinue if swelling, rash, or fever develops

Discontinue if irritation, pain, or redness persist or worsens, or if symptoms do not improve in 7 days

Do not use for >7 days unless directed by physician

 

Pregnancy and lactation

Pregnancy category: C

Lactation: not known if distributed in milk

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of CVS Bacitracin With Pain Relief (bacitracin and lidocaine topical)

Mechanism of action

Bacitracin: Inhibits bacterial cell wall synthesis, by preventing the incorporation of amino acids and nucleotides into the cell walL

Lidocaine: Topical anesthetics that reversibly block nerve conduction near their site of administration, thereby producing temporary loss of sensation in a limited area

 

Absorption

Bacitracin: Not substantially absorbed from intact or denuded skin, wounds, or mucous membranes

Lidocaine: Skin and mucosal absorption is highly variable; most anesthetic agents exist as solids and are only superficially absorbed through intact skin