undecylenic acid and derivatives (Cruex, Caldesene, Blis-To-Sol powder, Desenex soap, Fungoid AF, Fungicure Maximum Strength Liquid, Fungi-Nail, Gordochom, Hongo Cura)
Classes: Antifungals, Topical
Dosing and uses of Cruex, Caldesene (undecylenic acid and derivatives)
Adult dosage forms and strengths
powder
- 10%
- 12%
- 19%
topical solution/spray
- 25%
cream
- 20%
ointment
- 25%
soap
- 97.5g bar
Fungal Infection of the Skin
Indicated for superficial dermal fungal infections, typically used for tinea corporis and tinea pedis
Apply thin layer to clean dry skin BID or as directed; continue use for up to 4 wk
Pediatric dosage forms and strengths
powder
- 10%
- 12%
- 19%
topical solution
- 25%
cream
- 20%
soap
- 97.5g bar
Fungal Infection of the Skin
Indicated for superficial dermal fungal infections, typically used for tinea corporis and tinea pedis
<2 years: Safety and efficacy not established
2 years or older: As adults; Apply thin layer to clean dry skin BID or as directed; continue use for up to 4 wk
Cruex, Caldesene (undecylenic acid and derivatives) adverse (side) effects
Frequency not defined
Skin sensitivity
Warnings
Contraindications
Hypersensitivity
Cautions
Discontinue is skin irritation occurs
For external use only
Avoid contact with eyes
Pregnancy and lactation
Pregnancy category: C
Lactation: Unknown whether distributed in breast milk, caution advised
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Cruex, Caldesene (undecylenic acid and derivatives)
Mechanism of action
Antifungal agent
