Dosing and uses of Cromolyn sodium, ophthalmic, Crolom, Opticrom
Adult dosage forms and strengths
ophthalmic solution
- 4% (10mL)
Conjunctivitis
1-2 gtt in each eye 4-6 times/day at regular intervals
Symptom relief evident within a few days, but longer treatment (up to 6 weeks) may be required
Pediatric dosage forms and strengths
ophthalmic solution
- 4% (10mL)
Conjunctivitis
<4 years
- Safety and efficacy not established
>4 years
- 1-2 gtt in each eye 4-6 times/day at regular intervals
- Symptom relief evident within a few days, but longer treatment (up to 6 weeks) may be required
Cromolyn sodium, ophthalmic, Crolom, Opticrom adverse (side) effects
Frequency not defined
Transient burning/stinging upon instillation
Dryness around the eyes
Puffy eyes
Eye irritation
Watery eyes
Rash
Styes
Itchy eyes
Dyspnea
Warnings
Contraindications
Hypersensitivity to product or components
Cautions
Transient burning/stinging upon instillation
Do not exceed frequency of administration
Severe anaphylxis reactions may occur (rare)
Transient burning or stinging may occur with ophthalmic use
Symptoms may occur when tapering or wihdrawing the drug
Pregnancy and lactation
Pregnancy category: B
Lactation: Unknown whether distributed in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Cromolyn sodium, ophthalmic, Crolom, Opticrom
Mechanism of action
Mast cell stabilizer; inhibits histamine and SRS-A from mast celL
