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salicylic acid topical (Compound W, Compound W for Kids, Dr. Scholl's Advanced Pain Relief Corn Removers, Dr. Scholl's Callus Removers, Dr. Scholl's Clear Away, Dr. Scholl's Clear Away OneStep, Dr. Scholl's Clear Away Plantar, Dr. Scholl's Corn Removers, Dr. Scholl's Moisturizing Corn Remover Kit, Dr. Scholl's OneStep Corn Removers, DuoPlant, Durasal, Keralyt, Mediplast, Trans-Ver-Sal AdultPatch, Trans-Ver-Sal PediaPatch, Trans-Ver-Sal PlantarPatch, Sal-Acid, Virasal, Psoriasin Medicated Wash)

 

Classes: Keratolytic Agents

Dosing and uses of Compound W, Compound W for Kids (salicylic acid topical)

 

Adult dosage forms and strengths

topical liquid

  • 6%
  • 12.6%
  • 15%
  • 17%
  • 26%
  • 27.5%
  • 40%

topical wash

  • 3% (Psoriasin Medicated Wash)

 

Plantar Warts/Calluses/Corn

Hydrate skin prior to application by soaking in warm water for 5 min, then dry skin thoroughly

Liquid: Protect surrounding unaffected skin with petrolatum, then apply liquid to hyperkeratotic area

Patches/plasters/strips: Apply as directed per individual product

Product content varies, check individual labeling

 

Seborrheic Dermatitis/Psoriasis

Keratolytic for treating skin/scalp seborrhea or psoriasis

Psoriasin Medicated Wash: Apply at least twice weekly; rinse off after several minutes and then repeat

 

Pediatric dosage forms and strengths

topical liquid

  • 6%
  • 12.6%
  • 15%
  • 17%
  • 26%
  • 27.5%
  • 40%

 

Plantar Warts/Calluses/Corn

Hydrate skin prior to application by soaking in warm water for 5 min, then dry skin thoroughly

Liquid: Protect surrounding unaffected skin with petrolatum, then apply liquid to hyperkeratotic area

Patches/plasters/strips: Apply as directed per individual product

Product content varies, check individual labeling

 

Compound W, Compound W for Kids (salicylic acid topical) adverse (side) effects

Frequency not defined

Stinging/burning of skin

Desquamation

 

Warnings

Contraindications

Hypersensitivity

Prolonged use or application to large areas (risk for salicylism)

 

Cautions

Topical use only

Avoid contact with eyes

Caution in infants, diabetics, or those with impaired circulation

 

Pregnancy and lactation

Pregnancy category: C

Lactation: unknown

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Compound W, Compound W for Kids (salicylic acid topical)

Mechanism of action

Keratolytic agent