glycerin rectal (Colace Infant/Child Suppositories, Colace Suppositories, Fleet Glycerin Suppositories, Fleet Liquid Glycerin Suppositories, Pedia-Lax Glycerin Suppositories, Pedia-Lax Liquid Glycerin Suppositories)
Classes: Laxatives, Osmotic
Dosing and uses of Colace Infant/Child Suppositories, Colace Suppositories (glycerin rectal)
Adult dosage forms and strengths
liquid suppository
- 5.6g/5.5mL
suppository
- 2g
- 2.1g
Occasional Constipation
suppository
- 2-2.1 g suppository inserted in rectum, retain for about 15 min
liquid suppository
- 5.6 g liquid suppository inserted in rectum; retain for about 15 min
Maximum: 1 suppository or liquid suppository/day
Administration
Patient should lie on left side with knees bent
Remove protective wrap before inserting
Gently insert tip into rectum with slight side-to-side movement (tip of suppository pointing toward navel)
For liquid suppository, squeeze bulb until all liquid is expelled and discard unit
Pediatric dosage forms and strengths
liquid suppository
- 2.3g/2.3mL
- 5.6g/5.5mL
suppository
- 1g
- 1.2g
- 2g
- 2.1g
Occasional Constipation
suppository
- 2-5 years: 1-1.2 g suppository inserted in rectum, retain for about 15 min
- >5 years: 2-2.1 g suppository inserted in rectum, retain for about 15 min
liquid suppository
- 2-5 years: 2.3 g pediatric liquid suppository inserted in rectum; retain for about 15 min
- >5 years: 5.6 g liquid suppository inserted in rectum; retain for about 15 min
Maximum: 1 suppository or liquid suppository/day
Administration
Patient should lie on left side with knees bent
Remove protective wrap before inserting
Gently insert tip into rectum with slight side-to-side movement (tip of suppository pointing toward navel)
For liquid suppository, squeeze bulb until all liquid is expelled and discard unit
Colace Infant/Child Suppositories, Colace Suppositories (glycerin rectal) adverse (side) effects
Frequency not defined
Rectal discomfort
Burning sensation
Warnings
Contraindications
Hypersensitivity
Cautions
Do not use when abdominal pain, nausea, or vomiting present (unless directed by physician)
Frequent or prolonged use of laxatives may result in dependence
Rectal bleeding or failure to have bowel movement requires physician care
Contact physician before use if sudden change in bowel habits that last >2 wk
Do not use for longer than 1 wk
Pregnancy and lactation
Pregnancy category: C
Lactation: unknown, but probably compatible with breastfeeding
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Colace Infant/Child Suppositories, Colace Suppositories (glycerin rectal)
Onset: 15-60 min
Mechanism of action
Hyperosmotic laxative; attracts water into stool and elicits bowel movement
