Dosing and uses of Coenzyme R, vitamin H (biotin)
Daily Dietary Requirements
Adequate Intake: 30 mcg/day
Nursing Women: 35 mcg/day
Other Indications & Uses
Biotin deficiency (extremely rare), brittle fingernails, diabetes, alopecia
Pediatric dosage forms and strengths
Daily Dietary requirements
Infants (0-1 year old): 5-6 mcg/day
Children (1-9 years old): 8-12 mcg/day
Adolsescents (9-18 years old): 20-25 mcg/day
Coenzyme R, vitamin H (biotin) adverse (side) effects
Frequency not defined
Generally safe
Doses of 10 mg per day have been taken with no adverse effects
Warnings
Cautions
Hypersensitive individuals
Wating too much raw egg white (contains avidin that binds biotin)
Pregnancy and lactation
Pregnancy category: Not studied
Lactation: Not studied
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Nutrition
Sources: liver, legumes, tomatoes, soybeans, carrots
Function: member of water-soluble vitamin family, serves as cofactor to several carboxylases
Deficiency is extremely rare, may cause dermatitis, alopecia, perosis
Pharmacology of Coenzyme R, vitamin H (biotin)
Metabolism: liver
Excretion: kidney
