naphazoline/glycerin ophthalmic (Clear Eyes Cooling Comfort Redness Relief)
Classes: Decongestants, Ophthalmic
- Dosing and uses of Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic)
- Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic) adverse (side) effects
- Warnings
- Pregnancy
- Pharmacology of Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic)
Dosing and uses of Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic)
Adult dosage forms and strengths
naphazoline/glycerin
ophthalmic solution
- 0.03%/0.5%
Ocular Vasoconstrictor/Decongestant
Temporary relief of ocular redness caused by irritation and relief of burning or irritation caused by dry eyes
1-2 gtt to affected eye q3-4hr up to QID PRn
Not to exceed 72 hours of use
Pediatric dosage forms and strengths
naphazoline/glycerin
ophthalmic solution
- 0.03%/0.5%
Ocular Vasoconstrictor/Decongestant
Temporary relief of ocular redness caused by irritation and relief of burning or irritation caused by dry eyes
1-2 gtt to affected eye q3-4hr up to QID PRn
Not to exceed 72 hours of use
Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic) adverse (side) effects
Frequency not defined
Blurred vision
Mild transient stinging and/or irritation
Mydriasis Increased or decreased intraocular pressure
Headache
Warnings
Contraindications
Do not use with MAO inhibitors
Narrow angle glaucoma
Hypersensitivity
Stop use if vision changes, eye pain, condition worsens
Cautions
Remove contact lenses before use
Use with caution in patients with hypertension, cardiovascular abnormalities, diabetes mellitus, hyperthyroidism, infection, or injury
Rare reports of hypertension, cardiac irregularities, nervousness, nausea, dizziness, weakness, and sweating
Pregnancy and lactation
Pregnancy category: C
Lactation: not known if distributed in milk
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Clear Eyes Cooling Comfort Redness Relief (naphazoline/glycerin ophthalmic)
Mechanism of action
Naphazoline: May stimulate a-adrenergic receptors of the sympathetic nervous system; may produce mydriasis when applied to the conjunctiva, but this effect is usually minimal with the concentrations used as ocular decongestants
Glycerin: Lubricant