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methylcellulose (Citrucel)

 

Classes: Laxatives, Bulk-Producing

Dosing and uses of Citrucel (methylcellulose)

 

Adult dosage forms and strengths

caplet

  • 500mg

powder

  • 2g/scoop

 

Constipation

2 caplets up to 6 times/day; not to exceed 12 caplets/day; follow each dose with 8 oz of water

Alternatively, 1 heaping tablespoon (2 g) in 8 oz water qDay to q8hr

 

Pediatric dosage forms and strengths

caplet

  • 500mg

powder

  • 2g/scoop

 

Constipation (6-11 Years Old)

<6 years

  • Safety & efficacy not established

6-12 years old

  • 1 caplet up to 6 times/day; not to exceed 6 caplets/day
  • 1 g (½ tablespoon) in 8 oz of cold water; may increase to 1 tablespoon q8hr

>12 years

  • 2 caplets up to 6 times/day; not to exceed 12 caplets/day; follow each dose with 8 oz of water
  • Alternatively, 1 heaping tablespoon (2 g) in 8 oz water qDay to q8hr

 

Citrucel (methylcellulose) adverse (side) effects

Frequency not defined

Flatulence

Impaction

Excessive bowel activity

 

Warnings

Contraindications

Hypersensitivity, bowel obstruction, symptoms of appendicitis or acute surgical abdomen, GI ulceration/adhesions, fecal impaction, dysphagia, rectal bleeding

 

Pregnancy and lactation

Pregnancy category: NA (supplement; not a drug)

Lactation: No data available; not absorbed, unlikely to pose risk in breastfeeding

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Citrucel (methylcellulose)

Mechanism of action

Bulk producing laxative

 

Pharmacokinetics

Metabolism: Not absorbed from GI tract