Dosing and uses of Children’s Emetrol (phosphoric acid/dextrose/fructose)
Adult dosage forms and strengths
Not indicated
Pediatric dosage forms and strengths
phosphoric acid/dextrose/fructose
oral solution
- (21.5mg/1.87g/1.87g)/5mL
Nausea
Indicated for relief of upset stomach associated with nausea
<2 years: Safety and efficacy not established 2-12 years: 5-10 mL PO; may repeat q15min until symptoms subsides
For maximum effectiveness do not dilute or drink fluids of any kind immediately before or after taking this product
Children’s Emetrol (phosphoric acid/dextrose/fructose) adverse (side) effects
Frequency not defined
Flatulence
Abdominal pain
Diarrhea
Warnings
Contraindications
Hereditary fructose intolerance
Cautions
Diabetes; product contains sugar
Antacids may alter gastric pH and interfere with absorption of some concurrent medications
Discontinue and contact physician if symptoms persist, return, or worsen
Pregnancy and lactation
Pregnancy category: C
Lactation: Unknown if distributed in human breast milk
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Children’s Emetrol (phosphoric acid/dextrose/fructose)
Mechanism of action
Phosphoric acid: Antacid; phosphorated carbohydrate solution which neutralizes stomach acid
Dextrose and fructose: Hyperosmolar carbohydrate solutions have a direct effect on the GI tract wall, resulting in reduced GI smooth muscle contraction
