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carbamide peroxide oral (Cankaid, Gly-Oxide, Orajel Perioseptic)

 

Classes: Oral Rinses

Dosing and uses of Cankaid, Gly-Oxide (carbamide peroxide oral)

 

Adult dosage forms and strengths

oral solution/liquid

  • 10%
  • 15%
  • 20%

 

Canker Sores or Gum Irritation

Apply several drops to affected area, expectorate after 2-3 minutes, Or

Place 10 drops on tongue, mix with saliva, swish in mouth for several minutes, then expectorate

May repeat up to 4 times/day

 

Oral Hygiene

Liquid 15%: Every day use; apply to toothbrush, cover with toothpaste, brush & expectorate

 

Pediatric dosage forms and strengths

oral solution/liquid

  • 10%
  • 15%
  • 20%

 

Canker Sores or Gum Irritation

Age >2 years: As adults; apply several drops to affected area, expectorate out after 2-3 minutes, Or

Place 10 drops on tongue, mix with saliva, swish in mouth for several minutes, then expectorate

May repeat up to 4 times/day

 

Oral Hygiene

15% liquid (age >2 years): As adults; every day use; apply to toothbrush, cover with toothpaste, brush & expectorate

 

Warnings

Contraindications

Hypersensitivity

 

Cautions

Overgrowth of opportunistic infections possible with prolonged use

Consult dentist or physician if severe or persistent oral inflammation persists

 

Pregnancy and lactation

Pregnancy category: C

Lactation: Not secreted into breast milk

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.