pramoxine/zinc acetate topical (Caladryl Clear)
Classes: Anesthetics, Topical; Antipruritics/Non-corticosteroid Topical
Dosing and uses of Caladryl Clear (pramoxine/zinc acetate topical)
Adult dosage forms and strengths
pramoxine/zinc acetate topicaL
topical lotion
- 1%/0.1%
Topical Pain
For the relief of itching, pain, discomfort and oozing and weeping caused by ivy, oak, sumac poisoning; minor cuts; insect bites
Apply to affected area q6-8hr PRn
Pediatric dosage forms and strengths
pramoxine/zinc acetate topicaL
topical lotion
- 1%/0.1%
Topical Pain
For the relief of itching, pain, discomfort and oozing and weeping caused by ivy, oak, sumac poisoning; minor cuts; insect bites
<2 years: Safety and efficacy not established
>2 years: Apply to affected area q6-8hr PRn
Caladryl Clear (pramoxine/zinc acetate topical) adverse (side) effects
Frequency not defined
Irritation
Pruritus
Warnings
Contraindications
Hypersensitivity
Cautions
For external use only
Do not use in eyes
Do not use on blistered or broken skin
If condition worsens, or if symptoms persist for longer than 7 days or clear up and occur again within a few days, discontinue and reassess therapy
Pregnancy and lactation
Pregnancy category: Undetermined, caution advised
Lactation: Unknown if excreted in breast milk, caution advised
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Caladryl Clear (pramoxine/zinc acetate topical)
Mechanism of action
Local anesthetic due to inhibition of conduction of nerve impulses from sensory nerves, resulting from an alteration of the cell membrane permeability to ions
Absorption
Onset: 3-5 min