pramoxine/zinc acetate topical (Caladryl Clear)

Dosing and uses of Caladryl Clear (pramoxine/zinc acetate topical)

• Adult
• Pediatric

 

Adult dosage forms and strengths

pramoxine/zinc acetate topicaL

topical lotion

• 1%/0.1%

 

Topical Pain

For the relief of itching, pain, discomfort and oozing and weeping caused by ivy, oak, sumac poisoning; minor cuts; insect bites

Apply to affected area q6-8hr PRn

 

Pediatric dosage forms and strengths

pramoxine/zinc acetate topicaL

topical lotion

• 1%/0.1%

 

Topical Pain

For the relief of itching, pain, discomfort and oozing and weeping caused by ivy, oak, sumac poisoning; minor cuts; insect bites

<2 years: Safety and efficacy not established

>2 years: Apply to affected area q6-8hr PRn

 

Caladryl Clear (pramoxine/zinc acetate topical) adverse (side) effects

Frequency not defined

Irritation

Pruritus

 

Warnings

Contraindications

Hypersensitivity

 

Cautions

For external use only

Do not use in eyes

Do not use on blistered or broken skin

If condition worsens, or if symptoms persist for longer than 7 days or clear up and occur again within a few days, discontinue and reassess therapy

 

Pregnancy and lactation

Pregnancy category: Undetermined, caution advised

Lactation: Unknown if excreted in breast milk, caution advised

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Caladryl Clear (pramoxine/zinc acetate topical)

Mechanism of action

Local anesthetic due to inhibition of conduction of nerve impulses from sensory nerves, resulting from an alteration of the cell membrane permeability to ions

 

Absorption

Onset: 3-5 min