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povidone iodine (Betadine)

 

Classes: Topical Antimicrobials

Dosing and uses of Betadine (povidone iodine)

 

Topical Antisepsis

Apply to clean wound PRn

 

Pediatric dosage forms and strengths

 

Topical Antisepsis

Apply to clean wound PRn

 

Betadine (povidone iodine) adverse (side) effects

Frequency not defined

Hypothyroidism in neonates (<28 do) after use by mother prior to delivery; use with caution in pregnancy, lactation & children

Severe pain on application

Irritation

Pruritic

Erythema

Edematous erythema

Acneform eruption

 

Warnings

Contraindications

Hypersensitivity

 

Pregnancy and lactation

Pregnancy category: B

Lactation: use caution

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Betadine (povidone iodine)

Kinetic info not applicable

 

Mechanism of action

Microbicidal; oxidizes cell constituents; iodinates proteins and inactivates them