Dosing and uses of Benzocaine/antipyrine
Adult dosage forms and strengths
benzocaine/antipyrine
otic solution
- (54mg/14mg)/mL
Removal of Cerumen
2-4 gtt in ear TID PRN for 2-3 days to help detach cerumen from wall of canaL
Acute Otitis Media
Fill canal with solution; moisten cotton pledget with solution and insert into meatus
Pediatric dosage forms and strengths
benzocaine/antipyrine
otic solution
- (54mg/14mg)/mL
Removal of Cerumen
2-4 gtts in ear TID PRN for 2-3 days to help detach cerumen from wall of canaL
Acute Otitis Media
Fill canal with solution; moisten cotton pledget with solution, insert into meatus
Benzocaine/antipyrine adverse (side) effects
Frequency not defined
Local hypersensitivity reaction
Temporary stinging/burning in ear canaL
Warnings
Contraindications
Sensitivity to either agent, perforated tympanic membrane
Pregnancy and lactation
Pregnancy category: C
Lactation: excretion in milk unknown; use with caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Benzocaine/antipyrine
Mechanism of action
Antipyrine elicits analgesic properties
Benzocaine is a local anesthetic agent
Administration
Instructions
May use for drying ear canal or relieving discomfort
May repeat q1-2hr until pain and congestion relieved
A saturated cotton pledgett may be inserted into meatus
