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elamipretide (Bendavia): Dosing and Uses

 

Classes: Neurologics, Other

Medically reviewed by Min Clinic Staff | Updated: January 2026

Dosing and uses of Bendavia (elamipretide)

 

Mitochondrial Myopathies

Pending FDA approval for primary mitochondrial myopathy, characterized by muscle weakness in patients with genetic mitochondrial diseases

 

Pharmacology of Bendavia (elamipretide)

Mechanism of action

Mitochondria-targeting peptide; free radical scavenger and antioxidant that penetrates the cellular and outer mitochondrial membranes, and targets cardiolipin, which is found exclusively in the inner mitochondrial membrane