Dosing and uses of Bendavia (elamipretide)
Mitochondrial Myopathies
Pending FDA approval for primary mitochondrial myopathy, characterized by muscle weakness in patients with genetic mitochondrial diseases
Pharmacology of Bendavia (elamipretide)
Mechanism of action
Mitochondria-targeting peptide; free radical scavenger and antioxidant that penetrates the cellular and outer mitochondrial membranes, and targets cardiolipin, which is found exclusively in the inner mitochondrial membrane
