Phytosterols (Bayer Heart Health Advantage, benecol margarine, cholestatin, stigmasterol)
Classes: Cardiovascular, Herbals
- Suggested dosing of Bayer Heart Health Advantage, benecol margarine (phytosterols)
- Suggested uses of Bayer Heart Health Advantage, benecol margarine (phytosterols)
- Bayer Heart Health Advantage, benecol margarine (phytosterols) adverse (side) effects
- Warnings
- Pregnancy
- Pharmacology of Bayer Heart Health Advantage, benecol margarine (phytosterols)
Suggested dosing of Bayer Heart Health Advantage, benecol margarine (phytosterols)
Hypercholesterolemia
1200 mg/day PO capsules
1-2 Tbs 1-3 times daily as functional foods (margarine, salad dressing)
Bayer Heart Health Advantage
- 12 years or older: 400 mg PO BID with meals
Benign Prostatic Hyperplasia
60 -130 mg/day PO divided BID/TID of beta-sitosteroL
Suggested uses of Bayer Heart Health Advantage, benecol margarine (phytosterols)
Hypercholesterolemia, Benign prostatic hyperplasia (BPH).
Efficacy
Proven effective in lowering LDL in conjunction with diet & exercise
Improves urinary symptoms with BPH
Bayer Heart Health Advantage, benecol margarine (phytosterols) adverse (side) effects
Frequency not defined
Xanthomatosis
Atherosclerosis in patients with sitosterolemia (very rare)
Warnings
Contraindications
N/A
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Bayer Heart Health Advantage, benecol margarine (phytosterols)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Plant-derived sterols; decr cholesterol absorption from small intestine