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bacitracin topical (Baciguent)

 

Classes: Antibacterials, Topical

Dosing and uses of Baciguent (bacitracin topical)

 

Adult dosage forms and strengths

ointment

  • 500unit/g

 

Dermal Infections (Superficial)

Apply ointment qDay-q8hr

 

Pediatric dosage forms and strengths

ointment

  • 500unit/g

 

Dermal Infections (Superficial)

Apply ointment qDay-q8hr

 

Baciguent (bacitracin topical) adverse (side) effects

Frequency not defined

Rash

Itching

Pain

Hypersensitivity reaction (rare)

 

Warnings

Contraindications

Hypersensitivity, atopic patients

 

Cautions

Preparations should not be used for longer than 1 wk unless directed by a physician

 

Pregnancy and lactation

Pregnancy category: C

Lactation: Excretion in milk unknown; use with caution

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Baciguent (bacitracin topical)

Mechanism of action

Inhibits bacterial cell wall synthesis, by preventing the incorporation of mucopeptides into the growing cell walL

 

Absorption

Not substantially absorbed from intact or denuded skin, wounds, or mucous membranes