Yohimbe (aphrodien, corynanthe yohimbi, corynine, johimbi, pausinystalia yohimbe, quebrachine)
Classes: Urology, Herbals
Suggested dosing of Aphrodien, corynanthe yohimbi (yohimbe)
Sexual Dysfunction
15-30 mg PO daily
Bark tincture: 5-10 gtt PO TId
Yohimbe bark: Potential for side effects
Numerous regimens available, follow mfct recommendations
Suggested uses of Aphrodien, corynanthe yohimbi (yohimbe)
Erectile dysfunction, sexual dysfunction (male or female), sexual dysfunction (SSRI-induced)
Efficacy
Possibly effective for impotence
Aphrodien, corynanthe yohimbi (yohimbe) adverse (side) effects
Anxiety, cardiac coduction disturbances, cardiac failure, dizziness, excitation, fluid retention, gastric intolerance, headache, hypertension, hypotension, insomnia, irritability, nausea/vomiting, paralysis, respiratory depression, salivation, sinusitis, tachycardia, tremor, urinary frequency
Warnings
Contraindications
Angina, anxiety, BPH, concomitant MAO inhibitors, concomitant sympathomimetic drugs, depression, diabetes mellitus, heart disease, hypertension, hypotension, kidney disease, liver disease, post-traumatic stress disorder, prostate inflammation, tyramine-containing foods
Cautions
Schizophrenia
Pregnancy and lactation
Pregnancy category: unsafe
Lactation: avoid use
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Aphrodien, corynanthe yohimbi (yohimbe)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Yohimbine is an alpha-2-adrenergic blocker
