Anamu (apacin, apazote de zorro, aposin, calcauchin, chasser vermine, Congo Root, douvant douvant, emeruaiuma, guinea hen leaf, guinea henweed, gully root, heuvo de gato, hierba de las gallinitas, kuan, kudjuruk, lemtewei, lemuru, mal pouri, mapurit, mucura, ocano, payche, Petiveria alliacea, verbena hedionda, verveine puante, zorillo)
Classes: Antimicrobials, Herbals; Oncology, Herbals
Suggested dosing of Apacin, apazote de zorro (anamu)
1000-1500 mg PO BID or as directed by Mfr
Suggested uses of Apacin, apazote de zorro (anamu)
Cancer, various infections
Efficacy
In vitro studies indicate cytotoxic effect on cancer cells
Animal studies indicate immunostimulatory and antiinfective effects
No clinical studies
Apacin, apazote de zorro (anamu) adverse (side) effects
Frequency not defined
May cause hypoglycemia
Warnings
Contraindications
Pregnancy
Cautions
Bleeding diathesis, concomitant anticoagulants
DM, hypoglycemia
Pregnancy and lactation
Pregnancy category: do not use
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Apacin, apazote de zorro (anamu)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Immunostimulatory and anticancerous; contains several putative antineoplastic chemicals (eg, dibenzyl trisulfide) but precise mechanism not known
