Dosing and uses of AmLactin, Lac Hydrin (ammonium lactate)
Adult dosage forms and strengths
cream/lotion
- 12%
Ichthyosis Vulgaris, Xerosis
Apply to affected areas & rub in thoroughly BId
Pediatric dosage forms and strengths
cream/lotion
- 12%
Ichthyosis Vulgaris, Xerosis
Apply to affected areas & rub in thoroughly BId
AmLactin, Lac Hydrin (ammonium lactate) adverse (side) effects
>10%
Erythema (20%)
Transient burning/stinging (33%)
Peeling (16%)
1-10%
Dry skin, itching
Irritation
Hyperpigmentation
Petechiae
Warnings
Contraindications
Hypersensitivity
Cautions
Application on abraded or broken skin, facial application
Minimize/avoid use in parts of body that are exposed to natural/artificial sunlight
Pregnancy and lactation
Pregnancy category: B
Lactation: use caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of AmLactin, Lac Hydrin (ammonium lactate)
Absorption: 6.1%
Mechanism of action
Alphahydroxy acids & their salts are felt to act as humectants when applied on skin
