Suggested dosing of all-trans lycopene, psi-carotene (lycopene)
General Dosing Guidelines
Pure comopound: 13-75 mg/day PO
Capsule: 10-30 mg BID PO
Prostate Cancer
15 mg BID PO
Oral Leukoplakia
4-8 mg/day PO
Specific lycopene supplement (LycoRed)
Preventing Exercise-induced Asthma
30 mg/day PO
Suggested uses of all-trans lycopene, psi-carotene (lycopene)
Cancer, preventing atherosclerosis, cardiovascular disease, prostate cancer, HPV infection, cataracts, asthma, antioxidant, & anti-inflammatory
Efficacy
Bladder & colon cancer: There is no association between lycopene and the risk of cancer
Cardiovascular disease: Conflicting studies; more studies are needed to determine effectiveness
Atherosclerosis: Insufficient information
Oral leukoplakia: Preliminary evidence suggests significant clinical response
Ovarian, pancreatic prostate, & lung cancer: Evidence suggests it may reduce risk
HPV: Research suggests that women with higher levels of lycopene cleared oncogenic HPV in an average of 8.5 months compared to 11-12 months in women with lower levels
all-trans lycopene, psi-carotene (lycopene) adverse (side) effects
None reported
Warnings
Contraindications
None reported
Pregnancy and lactation
Pregnancy category: avoid use
Lactation: avoid use
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of all-trans lycopene, psi-carotene (lycopene)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Antioxidant with particular affinity for prostate
