sodium citrate/citric acid (Albrights Solution, Bicitra, Cytra 2, Oracit, Shohls Solution)
Classes: Alkalinizing Agents
Dosing and uses of Albrights Solution, Bicitra (sodium citrate/citric acid)
Adult dosage forms and strengths
sodium citrate/citric acid
oral solution
- (500mg/334mg)/5mL
- (490mg/640mg)/5mL
Urine Alkalinization, Prevention of Nephrolithiasis
10-30 mL diluted in up to 6 oz water/juice PO PC & HS PRn
Follow with additional water if desired
Pediatric dosage forms and strengths
sodium citrate/citric acid
oral solution
- (500mg/334mg)/5mL
- (490mg/640mg)/5mL
Urine Alkalinization, Prevention of Nephrolithiasis
>2 years old: 5-15 mL diluted in up to 6 oz water/juice PO PC & HS PRn
<2 years old: based on physician's discretion
Follow with additional water if desired
Albrights Solution, Bicitra (sodium citrate/citric acid) adverse (side) effects
Frequency not defined
Diarrhea
Nausea
Vomiting
Stomach pain
Fluid retention
Warnings
Contraindications
Hypersensitivity
Renal impairment
Sodium-restricted diet
Cautions
High BP, kidney or liver dz, cardiac failure, toxemia of pregnancy, peripheral/pulmonary edema
Do not dilute in tomato juice
Pregnancy and lactation
Pregnancy category: C
Lactation: consult physician
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Albrights Solution, Bicitra (sodium citrate/citric acid)
Metabolism: to active bicarbonate
Excretion: urine
Mechanism of action
Alkalinizes urine; citrate binds with urinary calcium
