Suggested dosing of AE941, Neovastat (shark cartilage)
Follow manufacturer's protocoL
Commercial products suggest doses ranging from 500 mg-4.5 grams given PO in 2-6 divided doses daily
Suggested uses of AE941, Neovastat (shark cartilage)
Cancer prevention & treatment
Treatment of arthritis & psoriasis
AE941, Neovastat (shark cartilage) adverse (side) effects
Frequency not defined
Dark urine
Excessive fatigue
Extreme itchiness
Nausea
Vomiting or diarrhea
Pain or swelling in the upper right part of the abdomen
Yellowing of skin or white parts of eyes
Constipation
Dizziness
Dysgeusia
Low blood pressure
Nausea
Upset stomach
Vomiting
Weakness
Warnings
Contraindications
Pregnancy, lactation
Cautions
May contain heavy metal contaminants such as mercury & cadmium
Do not take in high doses or for long periods of time
Pregnancy and lactation
Pregnancy category: do not use
Lactation: do not use
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of AE941, Neovastat (shark cartilage)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Inhibits angiogenesis & interferes with matrix metalloproteases (MMPs) enzymes
